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Mendeley Ltd transcriptome sequencing data
Transcriptome Sequencing Data, supplied by Mendeley Ltd, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/transcriptomic+sequencing+data/data+sequencing/pm41801219-580-1-11
Average 86 stars, based on 1 article reviews
transcriptome sequencing data - by Bioz Stars, 2026-09
86/100 stars

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Related Articles

Spatial Transcriptomics:

Article Title: Identification of Hypoxia-ALCAM high Macrophage- Exhausted T Cell Axis in Tumor Microenvironment Remodeling for Immunotherapy Resistance.
Article Snippet: .. Spatial Transcriptomics: The prostate spatial transcriptomic data, including count matrices and images, were provided by Andrew Erickson et al. from the Mendeley database[24] Spatial transcriptomics of CRC were obtained from Genome Sequence Archive with accessible ID HRA000979[39] BRCA and OC spatial transcriptomic data were obtained from 10X genomics official website (https://support.10xgenomics. com spatial-gene-expression/datasets), ccRCC (GSE175540)[41] and SCC (GSE144240)[61] Spatial transcriptomics of 67 tumor tissues with covering 14 cancer types and with clear tumor boundaries were collected from the web available portal SpatialTME (https://www.spatialtme.yelab.site/)[62] Single-Cell Transcriptomics: Thirty-five single-cell transcriptomics datasets with metadata, 38 CD8+ T cells datasets and 34 CD4+ T cells datasets were obtained from Tumor Immune Single-cell Hub (TISCH)[45] To analyze T cell trajectory, we obtained human single-cell gene expression matrices from European Genome-phenome Archive (EGA) under study no. EGAS00001004809 and no. EGAD00001006608[63] For mouse T cells, we used single-cell expression matrices collected by Massimo Andreatta et al.[46] (https://github.com/carmonalab/ProjecTILs_CaseStudies). ..

Sequencing:

Article Title: Identification of Hypoxia-ALCAM high Macrophage- Exhausted T Cell Axis in Tumor Microenvironment Remodeling for Immunotherapy Resistance.
Article Snippet: .. Spatial Transcriptomics: The prostate spatial transcriptomic data, including count matrices and images, were provided by Andrew Erickson et al. from the Mendeley database[24] Spatial transcriptomics of CRC were obtained from Genome Sequence Archive with accessible ID HRA000979[39] BRCA and OC spatial transcriptomic data were obtained from 10X genomics official website (https://support.10xgenomics. com spatial-gene-expression/datasets), ccRCC (GSE175540)[41] and SCC (GSE144240)[61] Spatial transcriptomics of 67 tumor tissues with covering 14 cancer types and with clear tumor boundaries were collected from the web available portal SpatialTME (https://www.spatialtme.yelab.site/)[62] Single-Cell Transcriptomics: Thirty-five single-cell transcriptomics datasets with metadata, 38 CD8+ T cells datasets and 34 CD4+ T cells datasets were obtained from Tumor Immune Single-cell Hub (TISCH)[45] To analyze T cell trajectory, we obtained human single-cell gene expression matrices from European Genome-phenome Archive (EGA) under study no. EGAS00001004809 and no. EGAD00001006608[63] For mouse T cells, we used single-cell expression matrices collected by Massimo Andreatta et al.[46] (https://github.com/carmonalab/ProjecTILs_CaseStudies). ..

Single Cell:

Article Title: Identification of Hypoxia-ALCAM high Macrophage- Exhausted T Cell Axis in Tumor Microenvironment Remodeling for Immunotherapy Resistance.
Article Snippet: .. Spatial Transcriptomics: The prostate spatial transcriptomic data, including count matrices and images, were provided by Andrew Erickson et al. from the Mendeley database[24] Spatial transcriptomics of CRC were obtained from Genome Sequence Archive with accessible ID HRA000979[39] BRCA and OC spatial transcriptomic data were obtained from 10X genomics official website (https://support.10xgenomics. com spatial-gene-expression/datasets), ccRCC (GSE175540)[41] and SCC (GSE144240)[61] Spatial transcriptomics of 67 tumor tissues with covering 14 cancer types and with clear tumor boundaries were collected from the web available portal SpatialTME (https://www.spatialtme.yelab.site/)[62] Single-Cell Transcriptomics: Thirty-five single-cell transcriptomics datasets with metadata, 38 CD8+ T cells datasets and 34 CD4+ T cells datasets were obtained from Tumor Immune Single-cell Hub (TISCH)[45] To analyze T cell trajectory, we obtained human single-cell gene expression matrices from European Genome-phenome Archive (EGA) under study no. EGAS00001004809 and no. EGAD00001006608[63] For mouse T cells, we used single-cell expression matrices collected by Massimo Andreatta et al.[46] (https://github.com/carmonalab/ProjecTILs_CaseStudies). ..

Transcriptomics:

Article Title: Identification of Hypoxia-ALCAM high Macrophage- Exhausted T Cell Axis in Tumor Microenvironment Remodeling for Immunotherapy Resistance.
Article Snippet: .. Spatial Transcriptomics: The prostate spatial transcriptomic data, including count matrices and images, were provided by Andrew Erickson et al. from the Mendeley database[24] Spatial transcriptomics of CRC were obtained from Genome Sequence Archive with accessible ID HRA000979[39] BRCA and OC spatial transcriptomic data were obtained from 10X genomics official website (https://support.10xgenomics. com spatial-gene-expression/datasets), ccRCC (GSE175540)[41] and SCC (GSE144240)[61] Spatial transcriptomics of 67 tumor tissues with covering 14 cancer types and with clear tumor boundaries were collected from the web available portal SpatialTME (https://www.spatialtme.yelab.site/)[62] Single-Cell Transcriptomics: Thirty-five single-cell transcriptomics datasets with metadata, 38 CD8+ T cells datasets and 34 CD4+ T cells datasets were obtained from Tumor Immune Single-cell Hub (TISCH)[45] To analyze T cell trajectory, we obtained human single-cell gene expression matrices from European Genome-phenome Archive (EGA) under study no. EGAS00001004809 and no. EGAD00001006608[63] For mouse T cells, we used single-cell expression matrices collected by Massimo Andreatta et al.[46] (https://github.com/carmonalab/ProjecTILs_CaseStudies). ..

Gene Expression:

Article Title: Identification of Hypoxia-ALCAM high Macrophage- Exhausted T Cell Axis in Tumor Microenvironment Remodeling for Immunotherapy Resistance.
Article Snippet: .. Spatial Transcriptomics: The prostate spatial transcriptomic data, including count matrices and images, were provided by Andrew Erickson et al. from the Mendeley database[24] Spatial transcriptomics of CRC were obtained from Genome Sequence Archive with accessible ID HRA000979[39] BRCA and OC spatial transcriptomic data were obtained from 10X genomics official website (https://support.10xgenomics. com spatial-gene-expression/datasets), ccRCC (GSE175540)[41] and SCC (GSE144240)[61] Spatial transcriptomics of 67 tumor tissues with covering 14 cancer types and with clear tumor boundaries were collected from the web available portal SpatialTME (https://www.spatialtme.yelab.site/)[62] Single-Cell Transcriptomics: Thirty-five single-cell transcriptomics datasets with metadata, 38 CD8+ T cells datasets and 34 CD4+ T cells datasets were obtained from Tumor Immune Single-cell Hub (TISCH)[45] To analyze T cell trajectory, we obtained human single-cell gene expression matrices from European Genome-phenome Archive (EGA) under study no. EGAS00001004809 and no. EGAD00001006608[63] For mouse T cells, we used single-cell expression matrices collected by Massimo Andreatta et al.[46] (https://github.com/carmonalab/ProjecTILs_CaseStudies). ..

Expressing:

Article Title: Identification of Hypoxia-ALCAM high Macrophage- Exhausted T Cell Axis in Tumor Microenvironment Remodeling for Immunotherapy Resistance.
Article Snippet: .. Spatial Transcriptomics: The prostate spatial transcriptomic data, including count matrices and images, were provided by Andrew Erickson et al. from the Mendeley database[24] Spatial transcriptomics of CRC were obtained from Genome Sequence Archive with accessible ID HRA000979[39] BRCA and OC spatial transcriptomic data were obtained from 10X genomics official website (https://support.10xgenomics. com spatial-gene-expression/datasets), ccRCC (GSE175540)[41] and SCC (GSE144240)[61] Spatial transcriptomics of 67 tumor tissues with covering 14 cancer types and with clear tumor boundaries were collected from the web available portal SpatialTME (https://www.spatialtme.yelab.site/)[62] Single-Cell Transcriptomics: Thirty-five single-cell transcriptomics datasets with metadata, 38 CD8+ T cells datasets and 34 CD4+ T cells datasets were obtained from Tumor Immune Single-cell Hub (TISCH)[45] To analyze T cell trajectory, we obtained human single-cell gene expression matrices from European Genome-phenome Archive (EGA) under study no. EGAS00001004809 and no. EGAD00001006608[63] For mouse T cells, we used single-cell expression matrices collected by Massimo Andreatta et al.[46] (https://github.com/carmonalab/ProjecTILs_CaseStudies). ..



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Identification of core genes associated with macrophage immune training and heart failure. (A) Schematic overview of human-derived macrophage trained immunity model and <t>transcriptomic</t> profiling workflow ( GSE235897 ). (B) The volcano plot and (C) DEGs heatmap of hMDMs from trained (n=3) and untrained (n=3) samples in the macrophage-trained immunity dataset GSE235897 (|log2FC| ≥ 0.585, p < 0.05). (D) Sample clustering dendrogram of GSE135055 dataset based on gene expression profiles. (E) Scale-free topology fit index and (F) mean connectivity analysis across a range of soft-thresholding powers. (G) Cluster dendrogram of genes showing co-expression modules identified by WGCNA in database GSE135055 . (H) Module-trait heatmap values represent correlation coefficients between healthy controls and HF samples (* p < 0.05, ** p < 0.01). (I) Venn diagram showing the overlap among heart failure DEGs, trained-immunity DEGs, and WGCNA module genes.
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Image Search Results


Identification of core genes associated with macrophage immune training and heart failure. (A) Schematic overview of human-derived macrophage trained immunity model and transcriptomic profiling workflow ( GSE235897 ). (B) The volcano plot and (C) DEGs heatmap of hMDMs from trained (n=3) and untrained (n=3) samples in the macrophage-trained immunity dataset GSE235897 (|log2FC| ≥ 0.585, p < 0.05). (D) Sample clustering dendrogram of GSE135055 dataset based on gene expression profiles. (E) Scale-free topology fit index and (F) mean connectivity analysis across a range of soft-thresholding powers. (G) Cluster dendrogram of genes showing co-expression modules identified by WGCNA in database GSE135055 . (H) Module-trait heatmap values represent correlation coefficients between healthy controls and HF samples (* p < 0.05, ** p < 0.01). (I) Venn diagram showing the overlap among heart failure DEGs, trained-immunity DEGs, and WGCNA module genes.

Journal: Frontiers in Immunology

Article Title: Identification of MTURN as a trained immunity-related biomarker for heart failure via integrative transcriptomic machine learning analysis and experimental validation

doi: 10.3389/fimmu.2026.1739660

Figure Lengend Snippet: Identification of core genes associated with macrophage immune training and heart failure. (A) Schematic overview of human-derived macrophage trained immunity model and transcriptomic profiling workflow ( GSE235897 ). (B) The volcano plot and (C) DEGs heatmap of hMDMs from trained (n=3) and untrained (n=3) samples in the macrophage-trained immunity dataset GSE235897 (|log2FC| ≥ 0.585, p < 0.05). (D) Sample clustering dendrogram of GSE135055 dataset based on gene expression profiles. (E) Scale-free topology fit index and (F) mean connectivity analysis across a range of soft-thresholding powers. (G) Cluster dendrogram of genes showing co-expression modules identified by WGCNA in database GSE135055 . (H) Module-trait heatmap values represent correlation coefficients between healthy controls and HF samples (* p < 0.05, ** p < 0.01). (I) Venn diagram showing the overlap among heart failure DEGs, trained-immunity DEGs, and WGCNA module genes.

Article Snippet: For single-cell transcriptomic data, we accessed the SCP1303 project from the Broad Institute ( https://singlecell.broadinstitute.org/single_cell ), which includes raw scRNA-seq data from failing human hearts with dilated and hypertrophic cardiomyopathy.

Techniques: Derivative Assay, Gene Expression, Expressing

Five heart failure transcriptomic datasets were integrated with a macrophage-trained immunity model to identify immune-related biomarkers. Through DEGs analysis, WGCNA, CIBERSORT, and six machine learning algorithms, hub genes were prioritized with MTURN emerging as the top candidate. Its potential was further validated by scRNA-seq analysis, which confirmed MTURN enrichment in cardiac macrophages. Finally, MTURN expression was validated using previously published heart failure transcriptomic data and in vitro experiments.

Journal: Frontiers in Immunology

Article Title: Identification of MTURN as a trained immunity-related biomarker for heart failure via integrative transcriptomic machine learning analysis and experimental validation

doi: 10.3389/fimmu.2026.1739660

Figure Lengend Snippet: Five heart failure transcriptomic datasets were integrated with a macrophage-trained immunity model to identify immune-related biomarkers. Through DEGs analysis, WGCNA, CIBERSORT, and six machine learning algorithms, hub genes were prioritized with MTURN emerging as the top candidate. Its potential was further validated by scRNA-seq analysis, which confirmed MTURN enrichment in cardiac macrophages. Finally, MTURN expression was validated using previously published heart failure transcriptomic data and in vitro experiments.

Article Snippet: For single-cell transcriptomic data, we accessed the SCP1303 project from the Broad Institute ( https://singlecell.broadinstitute.org/single_cell ), which includes raw scRNA-seq data from failing human hearts with dilated and hypertrophic cardiomyopathy.

Techniques: Expressing, In Vitro